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Merge pull request #1150 from monarch-initiative/create-pull-request/patch
Update Resource Data
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frontend/src/resources/monarch-app-infopages.json

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"visual_explainer": "https://www.youtube.com/watch?v=HmFhTk0Bahs"
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},
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"upheno": {
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"about": "The Unified Phenotype Ontology (uPheno) framework is a community effort to provide an integration layer over domain-specific phenotype ontologies, as a single, unified, logical representation. uPheno comprises:\n\n- a system for consistent computational definition of phenotype terms using ontology design patterns, maintained as a community library \n- a hierarchical vocabulary of species-neutral phenotype terms under which their species-specific counterparts are grouped \n- mapping tables between species-specific ontologies\n",
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"about": "The Unified Phenotype Ontology (uPheno) framework is a community effort to provide an integration layer over domain-specific phenotype ontologies, as a single, unified, logical representation. uPheno comprises:\n\n- a system for consistent computational definition of phenotype terms using ontology design patterns, maintained as a community library \n- a hierarchical vocabulary of species-neutral phenotype terms under which their species-specific counterparts are grouped \n- mapping tables between species-specific ontologies\n\nuPheno is a framework for consistent and logical definition of phenotype categories using ontology design patterns that provides a hierarchical vocabulary of species-neutral phenotype terms under which their species-specific counterparts are grouped. The ontology design templates are based on shared features of existing phenotypic descriptions from various model organisms, and represent community consensus. The phenotype pattern template-adherent terms are adopted by species-specific ontologies, thereby contributing to the community-built uPheno framework. uPheno accelerates cross-species inference and computationally amenable comparative phenotype analysis. For example, the interoperable representation of heart phenotypes characterized by increased size, compared with wild-type in distinct species, such as zebrafish and humans, allows the cross-species identification of genes whose alleles can cause similar phenotypes. uPheno contextual hierarchy for increased size of the heart as displayed in the OLS.\n",
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"citation": "Matentzoglu, N., Bello, S. M., Stefancsik, R., Alghamdi, S. M., Anagnostopoulos, A. V., Balhoff, J. P., Balk, M. A., Bradford, Y. M., Bridges, Y., Callahan, T. J., Caufield, H., Cuzick, A., Carmody, L. C., Caron, A. R., de Souza, V., Engel, S. R., Fey, P., Fisher, M., Gehrke, S., Grove, C., Hansen, P., Harris, N. L., Harris, M. A., Harris, L., Ibrahim, A., Jacobsen, J. O. B., Köhler, S., McMurry, J. A., Munoz-Fuentes, V., Munoz-Torres, M. C., Parkinson, H., Pendlington, Z. M., Pilgrim, C., Robb, S. M., Robinson, P. N., Seager, J., Segerdell, E., Smedley, D., Sollis, E., Toro, S., Vasilevsky, N., Wood, V., Haendel, M. A., Mungall, C. J., McLaughlin, J. A., & Osumi-Sutherland, D. (2025). The Unified Phenotype Ontology: A framework for cross-species integrative phenomics. Genetics, 229(3), iyaf027. https://doi.org/10.1093/genetics/iyaf027",
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"contact": {
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"email": "jmcl@ebi.ac.uk",
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"tagline": "A framework for cross-species integrative phenomics",
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"title": "The Unified Phenotype Ontology",
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"title_short": "uPheno",
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"visual_explainer": "uPheno is a framework for consistent and logical definition of phenotype categories using ontology design patterns that provides a hierarchical vocabulary of species-neutral phenotype terms under which their species-specific counterparts are grouped. The ontology design templates are based on shared features of existing phenotypic descriptions from various model organisms, and represent community consensus. The phenotype pattern template-adherent terms are adopted by species-specific ontologies, thereby contributing to the community-built uPheno framework. uPheno accelerates cross-species inference and computationally amenable comparative phenotype analysis. For example, the interoperable representation of heart phenotypes characterized by increased size, compared with wild-type in distinct species, such as zebrafish and humans, allows the cross-species identification of genes whose alleles can cause similar phenotypes. uPheno contextual hierarchy for increased size of the heart as displayed in the OLS."
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"visual_explainer": null
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},
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"vbo": {
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"about": "The Vertebrate Breed Ontology (VBO) is an open, community-driven ontology representing over 19,500 livestock and companion animal breed concepts covering 49 species. Breeds are classified based on community and expert conventions (e.g., cattle breed) and supported by relations to the breed's genus and species indicated by National Center for Biotechnology Information (NCBI) Taxonomy terms. Relationships between VBO terms (e.g., relating breeds to their foundation stock) provide additional context to support advanced data analytics. VBO term metadata includes synonyms, breed identifiers/codes, and attributed cross-references to other databases.",

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