docs: update dataset creation and maintenance guides

data_output/community/isuvdl/mazeller/prrsv1/orf5/yimim2025/unreleased/CHANGELOG.md

@@ -0,0 +1,22 @@
+## Unreleased
+
+- Remove invalid `qc.missingData.scoreWeight` and `qc.mixedSites.scoreWeight`
+
+## 2025-09-09T12:13:13Z
+
+Add schema definition url to `pathogen.json`. This is a purely technical change, for convenience of dataset authors. The data itself is not modified.
+
+## 2025-03-26T14:04:54Z
+
+ - Clarified dataset name as PRRSV-1 ORF5
+ - Removed 'X' marking Lelystad as a vaccine
+
+
+## 2025-03-26T11:47:13Z
+
+Fix GFF3 format issues in genome annotation
+
+
+## 2025-03-12T21:00:00Z
+
+Initial release.

data_output/community/isuvdl/mazeller/prrsv1/orf5/yimim2025/unreleased/README.md

@@ -0,0 +1,30 @@
+# Betaarterivirus europensis 1 (PRRSV-1) based on reference M96262.2 (Lelystad)
+
+
+## Dataset attributes
+
+| attribute            | value                                    |
+| -------------------- | ---------------------------------------- |
+| name                 | PRRSV-1 ORF5 Lineages, Yim-im & Zhang 2025 Vet Microbiol  |
+| refName              | LEYPOLYENV                               |
+| refAccession         | M96262.2                                 |
+| refProtein		       | AAA46278.1                               |
+
+
+## Scope of this dataset
+
+This dataset is based on [Yim-im et al., 2025](https://doi.org/10.1016/j.vetmic.2025.110413) for defining PRRSV-1 lineages on a global scale. This 
+nomeclature builds upon the following past publications:
+1. [Shi et al., 2010](https://doi.org/10.1016/j.virusres.2010.08.014)
+2. [Balka et al., 2018](https://doi.org/10.1038/s41598-018-26036-w)
+3. [Lee et al., 2023](https://doi.org/10.3390/pathogens12060757)
+
+## Authors and contacts
+
+Maintainer: [Michael Zeller](mailto:mazeller@iastate.edu?subject=[Nextclade]%20PRRSV1)
+
+For questions regarding the dataset, please contact the corresponding author of [Yim-im et al., 2025](https://doi.org/10.1016/j.vetmic.2025.110413).
+
+## What is Nextclade dataset
+
+Read more about Nextclade datasets in Nextclade documentation: https://docs.nextstrain.org/projects/nextclade/en/stable/user/datasets.html

data_output/community/isuvdl/mazeller/prrsv1/orf5/yimim2025/unreleased/lelystad_orf5.fasta

@@ -0,0 +1,2 @@
+>lelystad_orf5
+ATGAGATGTTCTCACAAATTGGGGCGTTTCTTGACTCCGCACTCTTGCTTCTGGTGGCTTTTTTTGCTGTGTACCGGCTTGTCCTGGTCCTTTGCCGATGGCAACGGCGACAGCTCGACATACCAATACATATATAACTTGACGATATGCGAGCTGAATGGGACCGACTGGTTGTCCAGCCATTTTGGTTGGGCAGTCGAGACCTTTGTGCTTTACCCGGTTGCCACTCATATCCTCTCACTGGGTTTTCTCACAACAAGCCATTTTTTTGACGCGCTCGGTCTCGGCGCTGTATCCACTGCAGGATTTGTTGGCGGGCGGTACGTACTCTGCAGCGTCTACGGCGCTTGTGCTTTCGCAGCGTTCGTATGTTTTGTCATCCGTGCTGCTAAAAATTGCATGGCCTGCCGCTATGCCCGTACCCGGTTTACCAACTTCATTGTGGACGACCGGGGGAGAGTTCATCGATGGAAGTCTCCAATAGTGGTAGAAAAATTGGGCAAAGCCGAAGTCGATGGCAACCTCGTCACCATCAAACATGTCGTCCTCGAAGGGGTTAAAGCTCAACCCTTGACGAGGACTTCGGCTGAGCAATGGGAGGCCTAG

data_output/community/isuvdl/mazeller/prrsv1/orf5/yimim2025/unreleased/lelystad_orf5.gff

@@ -0,0 +1,4 @@
+##gff-version 3
+##sequence-region	lelystad_orf5	1	606
+lelystad_orf5	Geneious	extracted region	1	606	.	+	.	Name=Extracted region from LEYPOLYENV
+lelystad_orf5	Geneious	gene	1	606	.	+	0	Name=ORF5 CDS

data_output/community/isuvdl/mazeller/prrsv1/orf5/yimim2025/unreleased/pathogen.json

@@ -0,0 +1,54 @@
+{
+  "$schema": "https://raw.githubusercontent.com/nextstrain/nextclade/refs/heads/release/packages/nextclade-schemas/input-pathogen-json.schema.json",
+  "schemaVersion": "3.0.0",
+  "files": {
+    "reference": "lelystad_orf5.fasta",
+    "pathogenJson": "pathogen.json",
+    "genomeAnnotation": "lelystad_orf5.gff",
+    "examples": "sequences.fasta",
+    "readme": "README.md",
+    "changelog": "CHANGELOG.md",
+    "treeJson": "tree.json"
+  },
+  "alignmentParams": {
+    "penaltyGapOpen": 8,
+    "penaltyGapOpenInFrame": 12,
+    "penaltyGapOpenOutOfFrame": 14,
+    "gapAlignmentSide": "left",
+    "minSeedCover": 0.01,
+    "minLength": 400
+  },
+  "attributes": {
+    "name": "PRRSV-1 ORF5",
+    "reference name": "Porcine reproductive and respiratory syndrome virus 1, ORF5 cds",
+    "reference accession": "M96262.2"
+  },
+  "qc": {
+    "missingData": {
+      "enabled": true,
+      "missingDataThreshold": 2000,
+      "scoreBias": 500
+    },
+    "snpClusters": {
+      "enabled": true,
+      "windowSize": 100,
+      "clusterCutOff": 6,
+      "scoreWeight": 50
+    },
+    "mixedSites": {
+      "enabled": true,
+      "mixedSitesThreshold": 15
+    },
+    "frameShifts": {
+      "enabled": true,
+      "scoreWeight": 20
+    },
+    "stopCodons": {
+      "enabled": true,
+      "scoreWeight": 50
+    }
+  },
+  "version": {
+    "tag": "unreleased"
+  }
+}

data_output/community/isuvdl/mazeller/prrsv1/orf5/yimim2025/unreleased/sequences.fasta

@@ -0,0 +1,225 @@
+>MN368729
+ATGAAATGTTCTCACAAGTCGGGGCGTTCCTTGACTCCGCACTCTTGCTTTTGGTGGCTTTCTTTGCTGTGTATCGGCTT
+GTCTTGGTCCTTTGCCGATGGCAACGGCAACAGCTCGACATCCCAATACATATATAATTTGACGATATGCGAGCTGAATG
+GGACCRACTGGTTGTCCGGTCATTTTGATTGGGCAGTCGAAACCTTTGTGCTTTACCCAGTTGCCACTCATATCATTTCA
+CTGGGTTTTCTCACAACAAGCCATTTCCTTGATGCGCTCGGTCTCGGCGCTGTGTCCGCCACAGGATTCATTGGCAAGCG
+GTATGTACTTAGCAGCATGTACGGCGTTTGCGCCTTCGCGGCGTTCGTATGTTTTGTCATCCGTGCTGCTAAAAATTGCA
+TGGCTTGCCGCTATGCCCGCACCCGGTTTACCAACTTCATCGTGGACGACCGGGGAAGAATCCATCGATGGAAGTCTTCA
+ATAGTGGTGGARAAATTGGGCAAAGCTGAAGTCGGTGGTGACCTTGTCAACATTAAGCATGTTGTCCTCGAAGGGGTTAA
+AGCTCAACCTTTGACGAGGACTTCGGCTGAGCAATGGGAAGCCTAG
+>MN368741
+ATGAGATGTTCTCACAAATTGGGGCATTTCTTGATTCCGCACTCTTGCTTTTGGTGGCTTTTTTTGCTGTGTATCGGCTT
+GTCTTGGTCCTTTGCCGATGGCAACGGCAACAGCTCGACATACCAATACATATATAATCTGACGATATGCGAGCTGAATG
+GGACCGCCTGGTTGTCTAACCACTTTTATTGGGCAGTCGAGACCTTCGTGCTTTACCCGGTTGCAACCCACATTCTCTCA
+CTGGGTTTTCTTACGACAAGCCATCTTTTTGACGCGCTTGGTCTCGGCGCTGTGTCCGTCACAGGGTTTTACGACCAACG
+ATACGTACTCAGCAGTATTTACGGCGCTTGTGCCTTCGCAGCGCTAGTGTGTTTTGGTATCCGTGCTGCTAAAAATTGCA
+TGGCTTGCCGCTACGCCCGCACCCGGTTCACCAACTTCATCGTGGACGACCGGGGGAGGATTCATCGGTGGAGGTCCCCA
+ATAGTGGTGGAGAAACTCGGCAAAGCTGAAATTGGCGGCGACCTTGTCGCCATCAAACATGTCGTCCTCGAAGGGGTTAA
+AGCTCAACCCTTGACGAGGACTTCAGCTGAGCAATGGGAGGCCTAG
+>MN368750
+ATGAGATGTTCTCACAAGTCGGGGCTTTTCTTGATTCCGCACTCTTGCTTCTGGTTGTTTTTTTTGTTGTGTACCGGCTT
+GTCCTGGTCCTTTGCCGATGGCAACGGCAACAGCTCGACATACCAATATATATATGACTTGACGATATGCGAGCTGAATG
+GAACCACCTGGTTGTCCGGCCATTTTGATTGGGCGGTTGAGACCTTTGTGCTTTACCCGGTTTTAACTCACATCCTCTCA
+CTGGGTTTTCTCACAACGAGTCATTTTTTTGATGCACTTGGTCTCAGCGCCGTGTCCATCATAGGATTTTGTGACGGCCG
+GTATGTACTCAGTAGTGTGTACGGCATTTGTGCTTCTGCTGCGCTCATTTGCTTTGTTATCCGTACTGCTAAAAATTGCA
+TGGCTTGTCGCTATGCTCGCACCCGGTTCACCAACTTCATTGTGGACGACCGAGGGGGAGTTCATCGGTGGAAGTCCCCA
+ATAGTGGTGGAGAAATCAGGCAAAGCTGAGGTTGGCAATACTCTTGTTAGCATCAAGCATGTCGTCATCGAAGGGGTAAA
+AGCTCAACCTTTAACAAGGACCTCAGCTGAGCAATGGCAGGCCTAG
+>MN368757
+ATGAGATGTTCTCACAAATTGGGGCGTTTCTTGACTCCTCACTCCTACTCCTGGTGGCTTTCTTTGCTGTGTACCGGCTT
+GTTCTGGTCCTTTGCCAACGGCAACGGCAACAGCTCGACACGCCAATACATATATAACTTGACGGTATGTGAGCTGAATG
+GGACCGGCTGGCTGTCCAATCATTTCAACTGGGCTGTCGAAGCCTTTGTGCTTTACCCGGTTGCCACTCATATTCTTTCA
+CTGGGTTTTCTCACGACAAGCCATTTCTTTGATGCTCTTGGTCTCAGCGCTGTATCCGCTACAGGATTTGCTAGCGGGCG
+GTATGTACTCAGCAGCGTGTATGGCGCCTGCGCCCTCGCGGCGCTCGTGTGCTTTGTCATCCGTGCTGCCAAAAATTGCA
+TGGCTTGCCGTTATGCCCGCACCCGGTTCACCAACTTCATCGTGGACGATCGGGGGAGGATCTACCGATGGAAGTCTCCA
+ATAGTGGTAGAGAAGTTGGGCAAAGCCCAAGTCGGTAGTGACCTTGTCACCATCAAACATGTCGTCCTTGAAGGGGTTAA
+AGCTCAACCCTCAACGAGGACTTCGGCTGAGCAATGGGAAGCCTAG
+>MN368758
+ATGAGATGTTCTCACAAATTGGGGCGTTTCTTGACTCCGCACTCTTGCTTTTGGTGGCTTTTTTTGCTGTGTACCGGCTT
+GTCCTGGTCCTTTGCCGATGGCAACGACAACAGCTCGACATACCAATACATATATAACCTGACGATATGCGAGCTGAATG
+GGACCGATTGGYTGTCCGGCCACTTTTCTTGGGCAGTCGAGACTTTTGTGTTATACCCGGTTGCAACTCACATTCTCTCA
+CTGGGTTTTCTCACAACAAGCCATTTCTTTGATGCGCTCGGTCTTGGCGCTGTGTCCGTCACAGGGTTCTACGGCAGACG
+GTATGTACTYAGCAGCGTCTACGGCACTTGTGCCTTCGCAGCGCTCGTGTGCTTTGTTATTCGCGCTGCTAAAAATTGCA
+TGGCCTGCCGTTATGCCCGTACCCGATTTACTAACTTCATTGTGGATGACCGGGGGACAGTTCACCGATGGAAGTCTCCA
+GTCGTGGTGGAAAAAATGGGCAAGGCCGAAGTCAGCGGCAATCTTGTCAACATTAAGCATGTCATCCTCGAAGGGGTTAA
+AGCTCAACCCTTGACAAGGACCTCAGCTGAACAATGGGAGGCATAG
+>MN368771
+ATGAGATGTTCTCACAAATTGGGGCGTTTCTTGACTCCGCACTCTTGCTTCTGGTGGTTTTTTTTGCTGTGTACCGGCTT
+GTCCTGGTCCTTTGGCGATGGCAACGGCAACAGCTCGACATACCAATACATATATAACTTGACGATATGCGAGCTGAATG
+GGACCGACTGGTTGTCCAGCCATTTTGGTTGGGCAGTCGAGACCTTTGTGTTTTACCCGGTTGCCACTCATATCCTCTCA
+CTGGGTTTTCTCACAACAAGCCATTTTTTTGACGCGCTCGGTCTCGGCGCTGTATCCACTGCAGGATTTGTTGGCGGGCG
+GTATGTACTCTGCAGCGTCTACGGCGCTTGTGCTTTCGCAGCGTTCGTATGTTTTGTCATCCGTGCTGCTAAAAATTGCA
+TGGCCTGCCGCTATGCCCGTACCCGGTTTACCAACTTCATTGTAGACAACCGGGGGAGAGTTCATCGATGGAAGTCTCCA
+ATAGTGGTAGAAAAATTGGGCAAAGCCGAAGTCGACGGCAACCTCGTCACCATCAAACATGTCGTCCTCGAAGGGGTTAA
+AGCTCAACCCTTGACGAGGACTTCGGCTGAGCAATGGGAGGCCTAG
+>MN368790
+ATGAGATGTTCTCACAAATCGGGGTGTTTCTTGACTCCGCACTCTTGCTTTTGGTGGTTTTTTTTGCTGTGTACCGGCTT
+GTCCTGGTCCTTTGCCGATGGCAACGGCAACAGCTCGACATACCAATATATATATAACTTGACGATATGCGAGCTGAATG
+GGACCGAATGGCTGTCTGACCATTTTAATTGGGCAGTCGAGACTTTTGTGCTCTACCCAGTGGCGACTCATATCCTCTCA
+CTGGGTTTCCTCACGACAAGTCATTTCCTTGATGCGTTCGGTCTTGGAGCTGTGTCAATTACAGGGTTTTGTGGCGGGCG
+GTACGTGCTCAGCAGCGTGTACGGCGCTTGTGCACTAGCAGCGCTCGTATGTTTTGTTATCCGTGCTGCCAAAAATTGTA
+TGGCTTGCCGCTATGCTCGTACCCGGTTTACCAACTTCATTGTGGATGACCGGGGGAGAATCCATCGGTGGAGGTCTCCA
+ATAGTGGTGGAAAAATTAGGTAAAGCTGACGTCGGCGGCGACCTTGTCACCATCAAACATGTCATCCTCGAAGGAGTCAA
+AGCTCAACCCTTGACGAGGACTTCGGCCGAGCAATGGGAGGCCTAG
+>MN368791
+ATGAGATGTTCTCACAAGTCGGGGCTTTCCTTGACTCCGCACTCTTGCTTCTGGTTGCTTTTTTTCTTGTGTACCGGCTT
+GCCCTGGCCCTTTGCCGATGGCAGCGGCAACAGCTCGACATACCAATACATATATAATTTGACGATATGCGAGCTGAATG
+GGACCAAATGGTTGTCCGGTCATTTTGATTGGGCAGTCGAAACCTTTGTGCTTTACCCAGTTGTCACTCATATCATTTCA
+CTGGGTTTTCTCACAACAAGCCATTTCCTTGATGCGCTCGGTCTCGGCGCTGTGTCCGCCACAGGATTCATTGGCGAGCG
+GTATGTACTTAGCAGCATGTACGGCATTTGCGCCTTCGCGGCGTTCGTATGTTTTGTCATCCGTGCTGCTAAAAATTGCA
+TGGCTTGCCGCTATGCCCGCACCCGGTTTACCAACTTCATCGTGGACGACCGGGGAAGAATCCATCGATGGAAGTCTTCA
+ATAGTGGTGGAGAAATTGGGCAAAGCTGAAGTCGGTGGTGACCTTGTCAACATTAAGCATGTTGTCCTCGAAGGGGTTAA
+AGCTCAACCTTTGACGAGGACTTCGGCTGAGCAATGGGAAGCCTAG
+>MN368793
+ATGAGATGTTCTCACAAATTGGAGCGTTCATTGACTCCTCACTCCTACTCTTGGTGGCTTTCTTTGCTGTGTACCGGCTT
+GTTCTGGTTCTTTGTCAACGGCGACAACAGCAGCTCGACACACCAATACATATATAACTTAACGGTATGCGAGCTGAATG
+GGACCAATTGGCTTTCCGGTCATTTCAACTGGGCTGTCGAGGCCTTTGTGCTTTACCCGGTTGCCACTCATATTCTTTCA
+CTGGGTTTTCTCACGACAAGTCATTTCTTTGATGCCCTTGGTCTCTGTGCTGTGTCCGCCACAGGATTTGTTGGCGAGCG
+GTATGTACTCAGCAGCGTGTACGGCGCCTGCGCCCTTGCGGCGCTCGTGTGCTTTGTAATCCGTGCCGCTAAAAATTGCA
+TGGCTTGCCGTTATGCCCGCACCCGGTTCACCAACTTTATCGTAGACGATCGGGGGAGAATCCACCGATGGAAGTCTCCA
+ATAGTTGTAGAGAAGTTGGGCAAAGCTGAAGTCGGTAGTGACCTTGTTACCATCAAACACGTCGTCCTTGAAGGGGCTAA
+AGCTCAACCCTTAACGAGGACTTCAGCTGAGCAATGGGAAGCCTAG
+>MN368799
+ATGAGATGTTTTCACAAATTGGAGCGTTTCTTGACTCTTCACTCCTACTCCTGGTGGCTTTCTTTGCTGTGTACCGGCTT
+GTTCTGGTCCTTTGCCAACGGCGACGACAACAGCTCGACACGCCAATACATATATAACTTGACGATATGCGAGCTGAATG
+GGACCACCTGGCTATCCAATCATTTCGACTGGGCTGCCGAGGCCTTTGTGCTTTACCCGGTTGTTACTCATATTCTTTCA
+CTGGGTTTTCTCACGACAAGCCATTTCTTTGATGCTCTTGGTCTCAGCGCTGTATCCACTATAGGATTTGCTGGCGGGCG
+GTATGTACTCAGCAGCGTGTATGGTACCTGTGCCTTTGCGGCGCTCGTGTGCTTTGTCATCCGTGCTGCTAAGAATTGCA
+TGGCTTGCCGTTATGCCCGCACTCGGTTCACCAACTTCATCGTGGACGATCGGGGGAGGATCCACCGATGGAAGTCTCCA
+ATAGTGGTGGAGAAGTTGGGCAAAGCTGAAGTCGGTAATGACCTTGTCGCCATCAAACACGTCGTCCTTGAAGGGGTTAA
+AGCTCAACCCTTAACGAGGACTTCGGCTGAGCAATGGGAAGCCTAG
+>MN368801
+ATGAGATGTTCTCACAAATCGGGGTGTTTCTTGACTCCGCACTCTTGCTTTTGGTGGTTTTTTTTGCTGTGTACCGGCTT
+GTCCTGGTCCTTTGCCGATGGCAACGGCAACAGCTCGACATACCAATATATATATAACTTGACGATATGCGAGCTGAATG
+GGACCAAGTGGCTGTCTGACCATTTTAATTGGGCAGTCGAGACTTTTGTGCTCTACCCAGTGGCGACTCATATCCTCTCA
+CTGGGTTTCCTCACGACAAGTCATTTCCTTGATGCGTTCGGTCTTGGAGCTGTGTCAATTACAGGGTTTTGTGACGGGCG
+ATACGTGCTCAGCAGCGTGTACGGCGCTTGTGCACTAGCAGCGCTCGTATGTTTTGTTATCCGTGCTGCCAAAAATTGTA
+TGGCTTGCCGCTATGCTCGTACCCGGTTTACCAACTTCATTGTGGATGACCGGGGGAGAATCCATCGGTGGAGGTCTCCA
+ATAGTGGTGGAGAAATTAGGTAAAGCTGACGTCGGCGGCGACCTCGTCACCATCAAACATGTCATCCTCGAAGGAGTCAA
+AGCTCAACCCTTGACGAGGACTTCGGCCGAGCAATGGGAGGCCTAG
+>MN368804
+ATGAGATGTTCTCACAAATTGGGGCGCTTCTTGACTCCGCACTCTTGCTTTTGGTGGCTTTTTTTGTTGTGTACCGGTTT
+GTCCTGGTCCTTTGCCGATGGCAACGGCAACAGCTCGACATACCAATACATATATAATTTGACGATATGCGAGCTGAATG
+GGACTGACTGGCTGTCCAACAAATTTTATTGGGCGGTCGAAACCTTTGTGCTTTACCCGGTGGCAACTCACATCCTTTCA
+CTGGGTTTTCTTACTACAAGCCACCTTTTTGATGCACTCGGTCTCGGAGCTGTGTCTATCACGGGATTCTGCGGTAGACG
+GTATGTGCTTAGCAGCGTGTACGGCACTTGTGCGTTCGCGGCGCTCGTGTGTTTTGTTATCCGTGCCGCAAAAAATTGTA
+TGGCCTGCCGCTATGCCCGTACACGGTTTACCAACTTCATTGTGGACGACCGGGGTGGAATCCATCGATGGAAGTCTCCA
+ATAGTTGTGGAGAAGTTGGGCAAAGCTGAAGTTGGCAATGCCCTCGTCACCATTAAGCATGTCGTCATCGAAGGAGCCGC
+CGCTCAACCCTTAACAAGGACCCCTGCTGAGCAATGGCAAGCCTAG
+>MN368819
+ATGAGATGTTCTCACAAATTGGGGCGCTTCTTGACTCCGCACTCTTGCTTTTGGTGGCTTTTTTTGTTATGTACCGGTTT
+GTCCTGGTCCTTTGCCGATGGCAACGGCAACAGCTCGACATACCAATACATATATAATTTGACRATATGCGAGCTGAATG
+GGACTGACTGGCTGTCCAACAAATTTCATTGGGCGGTCGAAACCTTTGTGCTTTACCCGGTGGCAACTCACATCCTCTCA
+CTGGGTTTTCTTACTACAAGCCACCTTTTTGATGCACTCGGTCTCGGAGCTGTGTCTATCACGGGATTCTGCGGTAGACG
+GTATGTGCTTAGCAGCGTGTACGGCACTTGTGCGTTCGCGGCGCTCGTGTGTTTTGTTATCCGTGCCGCAAAAAATTGTA
+TGGCCTGCCGCTATGCCCGTACACGGTTTACCAACTTCATTGTGGACGACCGGGGTGGAATCCATCGATGGAAGTCTCCA
+ATAGTTGTGGAGAAGTTGGGCAAAGCTGARGTTGGCAATGCCCTCGTCACCATTAAGCATGTCGTCATCGAAGGAGCCGC
+CGCTCAACCCTTAACAAGGACCCCTGCTGAGCAATGGCAAGCCTAG
+>MN368824
+ATGAGATGTTCTCACAAGTCGGGGCTTTTCTTGACTCCGCACTCTTGCTTCTGGCTGCTTTTTTTGTTGTGTACCGGCTT
+GTCCTGGTCCTTTGCCGCTGGCAACGGCAACAGCTCGACATACCAATACATATATAACTTGACGATATGTGAGCTGAATG
+GAACCACCTGGTTGTCCGCCCATTTTGATTGGGCGGTTGAGACCTTTGTGCTTTACCCGGTTTTAACTCACATCCTCTCA
+CTGGGTTTTCTCACAACRAGTCATCTTTTTGATGCACTTGGTCTCAGCGCCGTGTCCGTCATAGGATTTTATGACAGCCG
+GTATGTACTCAGTAGTGTGTACGGCATTTGCGCTTCCGCTGCGCTCATCTGCTTTGTTATCCGTACTGCAAAAAATTGCA
+TGGCTTGTCGCTATGCTCGCACCCGGTTCACTAACTTCATTGTGGACGACCGAGGGGGAGTTCATCGGTGGAAGTCCCCA
+ATAGTGGTGGAGAAATCAGGTAAAGCTGAGGTTGGCGATGCTCTTGTTACCATCAAGCACGTCGTCATTGAAGGGGTCAA
+AGCTCAACCTTTAACAAGGACCTCAGCTGAGCAATGGCAGGCCTAG
+>MN368838
+ATGAGATGTTCTCACAAATTGGAGCGTTTCTTGACTCCTCACTCTTGCTTCTGGTGGCTTTTTTTGCTTTGTACCGGCTT
+GTCTTGGTCCTTTGTCGATGGCAACGACAACAGCTCGACATACCAATACATATATAATTTGACGATATGCGAGCTGAATG
+GGACCGAATGGTTGACCAGCCATTTTGACTGGGCAGTCGAGACCTTTGTGCTTTACCCGGTTGCCACTCATATCCTTTCA
+CTGGGTTTTCTCACAACAAGCCATTTTTTTGATGCGCTCGGTCTCGGCGCTGTGTCCACTACAGGATTTGTTGGCGGGCG
+GTATGTACTCAGCAGCGTGTACGGCGCTTGTGCTTTCGCAGCGCTCGTATGTTTTGTCATCCGCGCTGCTAAAAATTGCA
+TGGCTTGCCGTTATGCCCGTACCCGGTTTACCAACTTCATTGTGGACGACCGGGGGAGGATCCATCGATGGAAGTCTCCA
+ATAGTGGTAGAGAAATTGGGCAAAGCTGAAGTCGGTGGCGACCTCGTCACCATCAAACATGTCGTCCTCGAAGGGGTTAA
+AGCTCAACCCTTGACGAGGACTTCGGCTGAGCAATGGGAAGCCTAG
+>MN368843
+ATGAAATGTTCTCACACATTGGAGCGTTTCTTGATTCCTCACTCTTATTGCTGGTGGCTTTTTTTGTTGTGTACCGGCTT
+GTCCTGGTCCTCTGCCGTTGGCAACGGCAACAGCTCGACATACCAATACATATATAACTTGACGATATGCGAGCTGAATG
+GGACCGCGTGGCTGTTCGGCCATTTCGATTGGGCAGTCGAAACCTTTGTGTTTTACCCGGTGGTGACTCACGTCCTCTCA
+CTGGGTTTTCTTACAACAAGCCATTTTTTTGACACACTCGGTCTTGGAGTTGTGTCTGCCGCAGGATTTCATGATGGGCG
+GTACGTGCTTAGCAGTGTGTACGGTGTTTGCGCGTTTGCAGCACTTATATGTTTTGTCATCCGTGTAACCCAAAACTGCA
+TGGCTTGCCGCTATGCTCGCACCCGGTTCACTAACTTCATTGTGGACGACCGGGGGAGGATCCACCGATGGAAGTCCCCG
+ATAGTGGTGGAGAGGTTAGGCAAAGCTGAAATTGGCAACAACCTTGTCACCATTAAACATGTTGTTCTCGGAGGAGTCAA
+AGCTCAACCTTTGACGAGGACTTCTGCTGAGCAATGGGAAGCATAG
+>MN368844
+ATGAGATGTTCTCACAAATTGGGGCGTTTCTTGACTCCTCACTCCTACTCCTGGTGGCTTTCTTTGCTGTCTACCGGCTT
+GTTCTGGTCCTTTGCCAACGGCAACGGCAACAGCTCGACACGCCAATACATATATGACTTGACGGTATGCGAGCTGAATG
+GGACCGACTGGCTGTCCAGTCATTTCAACTGGGCTGTCGAGGCCTTTGTGCTTTACCCGGTTGCCACTCATATTCTTTCA
+CTGGGTTTTCTCACGACAAGCCATTTCTTTGATGCTCTTGGTCTCAGCGCTGTATCCGCTACAGGATTTGCTGGCGGGCG
+GTATGTACTCAGCAGCGTGTATGGCGCCTGCGCCCTTGCGGCGCTCGTGTGCTTTGTCATCCGTGCTGCCAAAAATTGCA
+TGGCTTGCCGTTATGCCCGCACCCGGTTCACCAACTTCATCGTGGACGATCGGGGGGGGATCCACCGATGGAAGTCTCCA
+ATAGTGGTAGAGAAGTTGGGCAAAGCTGAAGTCGGTAGTGGCCTTGTCACCATCAAACATGTCGTCCTTGAAGGGGTTAA
+AGCTCAACCCTTGACGAGGACTTCAGCTGAGCAATGGGAAGCCTAG
+>MN368849
+ATGAAATGTTCTCACAAATTGGGGCGCTTCTTGATTCCGCACTCCTGCTTCTGGTGGCTTTTTTTTTTGTGTACCGGCTT
+GTCCTGGTCCTTTGCCGATGGCAACGGCAACAGCTCGACATACCAATACATATATAACTTGACGATATGCGAGCTGAACG
+GGACCGACTGGTTGGTCGGTCACTTTGACTGGGCAGTCGAGACTTTTGTGCTTTATCCAGTGGCTACTCACATCCTCTCA
+CTGGGTTTTCTTACAACAAGCCATTTTCTTGACGCGCTTGGTCTTAGTGCTGTATCCATCGCAGGATTTATTGGCAAACG
+GTATGTGCTCAGCAGTATTTATGGCGCTTGTGCTTTCGCGGCACTTGTGTGCTTTGTCATCCGTGCTGCCAAGAATTGCA
+TGGCCTGCCGCTATGCCCGTACCCGGTTTACCAACTTCATCGTAGACGACCGAGGGGGAGTCCACAGGTGGAAGTCTTCC
+ATAGTGGTAGAAAAGATGGGCAAAGCCGAGGTTGGCGGTAACCTCGTCAACATCAAACACGTCGTCCTCGAAGGAGTTAG
+AGCTCAACCCTTAACGAGGACTTCGGCTGAGCAATGGGAGGCCTAG
+>MZ318699
+ATGAAATGTTCTCACAGATTGGAGCGTTTCTCGACTCCGCACTCCTGCTTTTGGTGGCTTTTTTTCTTGTGTATCGGTTT
+GTCCTGGTCCTTTGCCGACGGCAGCGGCAACAGCTCGACATACCAATACATATATAACTTGACGATATGCGAGCTGAATG
+GGACCTACTGGCTGTTCGGCCATTTTGATTGGGCAGCCGAGACCTTTGTGTTTTATCCTGTTATGACCCATGTCATCTCA
+CTGGGTTTCCTTACAACAAGTCACCTTTTTGACATGCTCGGCCTCGGCGCCGTGTCCGCCATTGGATTTCTTGGCAAACG
+GTATGTGCTCAGCAGTGTGTACGGCACCTGTGCCTTTGCGGCACTCGTGTGTTTTGTTATCCGTGCTGCCAAGAATTGCA
+TGGCCTGTCGCTATGCCCGTACCCGGTTCACTAACTTCATCGTGGATGACCGGGGGATGATCCATCGATGGAAGTCCCCA
+ATAGTGGTGGAGAAGTTGGGCAAAGCTCAGATTGGCAGCGACCTTGTTACCATCAAACACGTCGTCCTCGAAGGGGTCAA
+AGCTCAACCATTAACGAAGACATCGGCTGAGCAATGGGAAGCCTAG
+>OP342621
+ATGAGATGTTCTCACAGGTCGGGGAATTTCTTGACTCCTCGCTCTTGCTTTTGGTGGCTTTTTTTGTCGTCTACCGTTTT
+ATCTTGGCCCTTTGCCGCTGCCGGCGGCAACAGCTCGACATACCAATACATATATAATCTGACAATATGTGAGCTGAATG
+GGACCCGTTGGCTATCAGATAAATTTGAGTGGGCCGTGGAGAGCTTTGTGTTCTACCCTGTGGTAACCCATATTCTTTCA
+TTGGGTTTCCTCACAACAAGTCATTTCTTTGACACGCTTGGCCTCGGGGTTGTGTCCATCACTGGATATTACGACCAGAG
+GTACGTGCTCAGCAGCATATACGGTGTTTGTGCACTGGCCGCGCTTGTGTGCTTCATTATTCGTGTCGCTAAGAACTTCA
+TGGCATGCCGCTATGCTCGCACCCGGTTCACCAATTTCATCGTGGATGACCGCGGCAGGATTCATCGGTGGAAGTCTCCA
+ATAGTGGTGGAAAAATTAGGCAAAGCCGAGGTTGGTGGTGACCTTGTCACCGTCAAACACGTTGTCCTCGAAGGGGTAAA
+AGCTCAACCTTTGGCTAGGACTTCGGCCGAGCAATGGGAGGCTTAG
+>OP342622
+ATGAGATGTTCTCTGAGATTGGGACGTTTCTCGACTCCTCACTCTTGCTCTTGGTTGCCTTTTTTGTTGTCTACCGGTTT
+ATTCTGGTCCTTTGCCGGTGCCAACGGCAACAGCTCGACACACCAATACATATATAATTTGACAATATGCGAGCTGAATG
+GGACCGCCTGGTTGCAAGGCAATTTTGGTTGGGCAGTGGAGAGCTTTGTGCTCTACCCTGTAGTAACACACATCCTCTCA
+TTGGGTTTTCTTACAACAAGCCATTTCTTTGACACGGTCGGCCTCGGAGTTGTGTCCACCGCCGGGTACTATCATGGGCG
+ATATGTGCTTAGTAGCATATACGGTGTTTGCACACTCGCTGCGTTCGTGTGTCTCATTGTCCGTGTGGTCAAGAACTGCA
+TGGCGTGCCGTTACGCCCGCACTCGGTTTACCAACTTCATTGTGAGCGACCGAGGGAAGGTTTACCGGTGGAAGTCTCCC
+ATAGTGGTGGAAAAACTGGGAAAGGCTGAGGTTGGCGGTGACCTTGTCACCATCAAACACGTTGTCCTTGAAGGGGTTAA
+AGCACTACCTTTGACCAAGACTTCGGCTGAGCAATGGGAAGCTTAG
+>OP342624
+ATGAGATGTTCTCACAAATTGGGGCGGCCCTTGACTCTTCACTTCTACTCCTGGTGGCTTTTTTTATTGTGTACCGGCTT
+GCCTTGGTCCTTTGTCGGTGGCAACGGCAACAGCTCGACATACCAATACATATATAACCTGACGATATGTGAGCTGAATG
+GGACCGATTGGTTATCCAGCCATTTTGATTGGGCGGTCGAGAGCTTTGTGTTTTACCCGGTGATGACACATATTCTTTCA
+CTGGGTTTCCTTACAACGAGCCATTTCTTCGACACGCTTGGCCTTGGAGCTGTATCTGCCGCCGGGTTTCACARTGGACG
+ATACGTGCTTAGCAGTATATATGGGATTTTTGCGCTTGCAGCGTTTGTGTGTTTCGTCATTCGTGTTGTCAAGAATTGCA
+TGGCATGCCGCTATGCCCGCACCCGCTTTACTAATTTCATTGTGGATGACCGGGGAAGGGTCCATCGGTGGAAATCTCCA
+ATAGTGGTGGAAAAACTGGGTAAGGCCGAAGTCGGCGGTAATCTTGTTACCGTCAAACATGTTGTTCTTGAAGGAGTCAA
+AGCTCAACCTTTGGCGAGGACTTCGGCTGACGAGTGGGAGGCCTAG
+>OP342626
+ATGACATGTTCTCACAAATTGGGGCAGCCCTTGATTCTTCACTCCTGCTCCTGGTGGTTTTTTTTCTTGTGTACCGGCTT
+GTCTTGGTCCTTTGCCGATGGCAACGGCAACAGCTCGACATACCAATATATATATAACTTGACAATATGTGAGCTGAATG
+GGACCCATTGGCTGTCCAGCCATTTTGATTGGGCGGTTGAAAGTTTTGTGTTTTACCCCGTGGTGACTCACGTTCTTTCA
+CTGGGTTTCCTCACAACAAGCCACTTCTTCGACACACTTGGTCTCGGGGCTGTATCTGCTGCAGGGTTCTATGACCAGCG
+GTATGTGCTCAGCAGCATATACGGCGTTTCTGCGCTTGCTGCGTTCGTGTGCTTTGTCATTCGTGCTGTCAAGAATTGCA
+TGGCGTGTCGGTATGCTCGCACCCGATTCACCAATTTTATTGTGGATGACCGGGGGAGGATTCATCGGTGGAAATCCCCA
+ATAGTGGTGGAGAAGTTGGGCAAGGCCGAGGTTGACGGTAATCTTGTTACTATCAAGCACGTTGTCCTCGAAGGAGTGAA
+AGCTCAACCTTTGACGAGAACCCCGGCTGAACAATGGCAAGCTTAG
+>OQ920888
+ATGACATGTTTTCACAAATTGGAGCATTCCTTGATTCCGCACTCTTGCTTCTGGTGGTTTTTTTTGCTGTGTACCGGCTT
+GTCTTGGTCCTTTGCCGATGGCAACGGCAACAGCTCGACATACCAATACATATATAACTTAACGATATGCGAGCTGAATG
+GGACCAACTGGTTGTCTGGTCACTTTGATTGGGCAGTCGAGATTTTTGTGCTTTATCCGGTAGTCACTCATATTCTCTCA
+CTAGGTTTTCTTACCACAAGCCATTTTTTTGATGCGCTCGGTCTTGGAGCCGTGTCTGTCGCAGGTTTTTGTGACAATCG
+ATATGTGCTCAGCAGCGTATATGGCACTTGCGCATTCGCAGCGCTCGTGTGCTTTGTCATTCGTGTTGCTAAAAACTGCA
+TGGCTTGCCGTTATGCCCGCACCCGGTTCACCAACTTCATTATCGACGACCGGGGAAGAATCCATAGATGGAAGTCCCCA
+ATAGTGGTGGAAAAATCAGGCAAGGCTGAGGTCGGTGGCGGTCTCGTCACCATTAAGCATGTTGTCCTCGAGGGGGTCAA
+AGCTCAACCCTTGATGAGAACTTCGGCAGAGCAATGGGAGGCTTAG
+>OQ920889
+ATGACATGTTTTCACAAATTGGAGCATTCCTTGATTCCGCACTCTTGCTTCTGGTGGTTTTTTTTGCTGTGTACCGGCTT
+GTCTTGGTCCTTTGCCGATGGCAACGGCAGCAGCTCGACATACCAATACATATATAACTTAACGATATGCGAGCTGAATG
+GGACCAACTGGTTGTCTAGTCACTTTGATTGGGCAGTCGAGATTTTTGTGCTTTATCCGGTAGTCACTCATATTCTCTCA
+CTGGGTTTTCTTACCACAAGCCATTTTTTTGATGCGCTCGGTCTTGGAGCCGTGTCTGTTGCAGGTTTTTGTGACAATCG
+ATATGTGCTCAGCAGCGTATATGGCACTTGCGCATTCGCAGCGCTCGTGTGCTTTGTCATTCGTGTTGCTAAAAACTGCA
+TGGCTTGCCGTTATGCCCGCACCCGGTTCACCAACTTCATTATCGACGACCGGGGAAGAATCCATAGATGGAAGTCCCCA
+ATAGTGGTGGAAAAATCAGGCAAGGCTGAGGTCGGTGGCGGTCTCGTCACCATTAAGCATGTTGTCCTCGAGGGGGTCAA
+AGCTCAACCCTTGATGAGAACTTCGGCAGAGCAATGGGAGGCTTAG