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A snakemake pipeline for the processing of in situ sequencing data. Provides improvements to stitching, alignment, and read calling all in a scalable and memory…
A python MIST inspired microscopy stitching library created to provide accurate stitching across many imaging cycles, with additional features such as differing…
Sequencing and statistical analysis for Rose, J.C., Popp, N.A., et al. 2020. Suppression of unwanted CRISPR/Cas9 editing by co-administration of catalytically i…
Analysis pipeline for manuscript "Multiplexed measurement of variant abundance and activity reveals VKOR topology, active site and human variant impact."
We developed Variant Abundance by Massively Parallel Sequencing (VAMP-seq), which simultaneously measures the effects of thousands of missense variants on prote…