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rezve66/README.md

👋 Hi, I'm Md. Rezve

🌾 Agricultural Scientist • 🧬 Computational Biology Researcher • 🔬 Integrative Omics Enthusiast

Bridging biology, biotechnology, and computation to develop sustainable solutions for agriculture and environmental challenges.

📊 GitHub Statistics

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🧑‍🔬 About Me

🎓 Graduate in Agriculture with research experience in plant pathology, plant breeding, microbiology, and biotechnology.

🔬 I work at the intersection of experimental biology and computational science, integrating bioinformatics, genomics, and machine learning to solve problems in agriculture and environmental sustainability.

🌱 My research interests include:

🔬 Research Interests

🌾 Crop Improvement & Plant Genetics

🧬 Integrative Omics (Genomics • Transcriptomics • Proteomics)

🦠 Plant–Pathogen Interactions & Disease Resistance

🧪 Biotechnology & Molecular Plant Breeding

🧫 Microbial Enzymes for Plastic Biodegradation

🧠 Machine Learning in Agriculture

📊 Bioinformatics & Computational Biology

🌍 Sustainable Agriculture & Environmental Biotechnology


🔬 Research Expertise

🌾 Plant Genetics & Breeding

  • EMS/SA mutagenesis in rice (BRRI dhan28)
  • Screening blast-resistant mutants against Pyricularia oryzae
  • SSR marker analysis and genetic diversity studies
  • Heritability estimation and BLUP-based breeding analysis
  • Trait network and yield driver analysis

🧬 Plant–Pathogen Interaction

  • Molecular characterization of fungal pathogens
  • Effector biology and virulence factors
  • Host defense response mechanisms
  • ITS-based phylogenetic and haplotype analysis

♻️ Environmental Biotechnology

  • Microbial degradation of LDPE plastics
  • Enzyme extraction and purification
  • Nano–enzyme synergistic degradation systems
  • Green synthesis of ZnO, CuO, CeO₂ nanoparticles

🧪 Sustainable Biomaterials

  • Mycelium-based biomaterials
  • Agricultural waste valorization
  • Bio-based sustainable materials

💻 Computational Biology & Bioinformatics

I develop reproducible computational workflows for biological data analysis.

🧬 Omics Analysis

  • RNA-Seq analysis pipelines
  • Differential gene expression analysis
  • Functional annotation & pathway enrichment
  • Genome-wide gene family analysis
  • Comparative genomics

🧪 Molecular Modeling

  • Molecular docking
  • Molecular dynamics simulation
  • Protein–ligand interaction analysis
  • Structure visualization

📊 Computational Genetics

  • Trait correlation analysis
  • Graphical Lasso trait networks
  • Partial correlation networks
  • Machine learning trait prediction

🛠️ Skills & Tools

Programming & Data Science

Python R Bash

Libraries:

Pandas • NumPy • SciPy • Scikit-learn • Matplotlib • Seaborn • ggplot2


Bioinformatics Tools

BLAST MAFFT MEGA Cytoscape

Other tools:

ClustalW • TBtools • InterProScan • KEGG • STRING


Molecular Modeling

AutoDock GROMACS PyMOL


📌 Featured Research Projects

🌾 Rice Genotype–Trait Network & Yield Driver Analysis

Computational breeding pipeline integrating:

  • BLUP estimation
  • Heritability analysis
  • Trait correlation analysis
  • Graphical Lasso networks
  • Machine learning trait prediction

🧬 Genome-wide Gene Family Analysis

Comprehensive evolutionary analysis of:

  • SPL transcription factor family
  • NB-LRR resistance genes

Analyses include:

  • phylogenetic reconstruction
  • conserved motif identification
  • gene structure analysis
  • chromosomal distribution

♻️ Microbial Plastic Biodegradation

Research on microbial degradation of plastic polymers using:

  • fungal enzyme systems
  • nanoparticle-enhanced degradation
  • SEM and FTIR characterization

Goal: eco-friendly plastic degradation technologies


🧫 ITS-Based Fungal Diversity Analysis

Population genetics of plant pathogens:

  • Alternaria destruens
  • Cochliobolus sativus

Methods:

  • ITS sequencing
  • haplotype network analysis
  • phylogenetic reconstruction

🌱 Current Research Focus

🔬 Integrative Biotechnology for Sustainability

My research integrates wet-lab experimentation with computational modeling.

Key directions:

🧬 Enzyme engineering for plastic degradation
🤖 Machine learning for biodegradation optimization
🧪 Nano–enzyme hybrid degradation systems
🌾 Genomics-assisted crop improvement


📊 GitHub Statistics


🌍 Research Vision

I aim to develop integrative biological solutions combining biotechnology, computational biology, and artificial intelligence to address global challenges in:

🌾 sustainable agriculture
♻️ environmental biotechnology
🧬 genomic science


📫 Connect With Me


Exploring biological systems through data, computation, and experimentation to build a sustainable future.

Pinned Loading

  1. Enzymatic-and-Physiological-Response-Analysis-in-Rice-Genotypes Enzymatic-and-Physiological-Response-Analysis-in-Rice-Genotypes Public

    R scripts for generating high-resolution plots of enzyme activity, chlorophyll content, electrolyte leakage, and disease scores in rice genotypes under different treatments and time points.

  2. Rice-leaf-pca-analysis Rice-leaf-pca-analysis Public

    Jupyter Notebook

  3. rice-trait-network-yield-drivers- rice-trait-network-yield-drivers- Public

    Reproducible pipeline for BLUP heritability, trait networks, and machine-learning yield driver identification in rice breeding populations.

    Python

  4. SSR-Marker-Analysis SSR-Marker-Analysis Public

    A reproducible Python pipeline for SSR marker analysis integrating genetic diversity estimation, population structure analysis, linkage disequilibrium networks, and genetic differentiation in crop …

    Jupyter Notebook