Overview This repository contains the code for the paper "Predicting essential proteins by integrating network topology, subcellular localization information, gene expression profile and GO annotation data". The paper focuses on predicting essential proteins in biological networks by combining various types of data, including network topology, subcellular localization information, gene expression profiles, and Gene Ontology (GO) annotations.
Citation If you find this code useful in your research, please cite the following paper:
Wei Zhang, Jia Xu, Xiufen Zou. Predicting essential proteins by integrating network topology, subcellular localization information, gene expression profile and GO annotation data. IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2020, 17(6):2053-2061.
@article{zhang2020predicting, title={Predicting essential proteins by integrating network topology, subcellular localization information, gene expression profile and GO annotation data}, author={Zhang, Wei and Xu, Jia and Zou, Xiufen}, journal={IEEE/ACM Transactions on Computational Biology and Bioinformatics}, volume={17}, number={6}, pages={2053--2061}, year={2020}, publisher={IEEE}, doi={10.1109/TCBB.2019.2893979} }
Requirements MATLAB software