The scripts implement a machine learning-augmented single-cell RNA sequencing analysis for identifying immature neurons in the human hippocampus across the lifespan and in Alzheimer's disease.

This notebook is related to the following publication: Zhou Y*, Su Y*, Li S*, Kennedy BC, Zhang DY, Bond AM, Sun Y, Jacob F, Lu L, Hu P, Viaene AN, Helbig I, Kessler SK, Lucas T, Salinas RD, Gu X, Chen HI, Wu H, Kleinman JE, Hyde TM, Nauen DW, Weinberger DR, Ming GL#, Song H#. Molecular landscapes of human hippocampal immature neurons across lifespan. Nature 607, 527-533 (2022). PMID: 35794479. https://doi.org/10.1038/s41586-022-04912-w