Skip to content

Commit 646cb66

Browse files
authored
Add scientific summary to README
Added a scientific summary section detailing the mechanism of action and components involved in the study.
1 parent ac051ab commit 646cb66

File tree

1 file changed

+20
-0
lines changed

1 file changed

+20
-0
lines changed

README.md

Lines changed: 20 additions & 0 deletions
Original file line numberDiff line numberDiff line change
@@ -29,5 +29,25 @@ This repository serves as an official timestamped record of invention for open s
2929

3030
---
3131

32+
## 🔬 Scientific Summary
33+
34+
### Mechanism of Action
35+
36+
| Component | Target | Function |
37+
| ------------------------- | -------------------- | ----------------------------------- |
38+
| Echinocandin (micafungin) | β-glucan synthase | Disrupts fungal cell wall synthesis |
39+
| β-1,3-Glucanase | Extracellular matrix | Liquefies polysaccharide ECM |
40+
| Ga³⁺ + EDTA | Metal metabolism | Iron substitution & chelation |
41+
42+
This tri-modal mechanism produces a **superlinear reduction** in residual viability:
43+
44+
\[
45+
\Phi_{\text{TCL}} = \eta_{\text{ech}} \cdot \eta_{\text{enz}} \cdot \left( 1 - \frac{[Fe^{3+}]_{\text{biofilm}}}{[Fe^{3+}]_0} \right)
46+
\]
47+
48+
Where the combined inhibition terms result in complete matrix collapse and ≥3-log biofilm reduction within 90 minutes.
49+
50+
---
51+
3252
## 🧩 Repository Structure
3353

0 commit comments

Comments
 (0)