Analysis code for:
Ector C, Didier J, De Landtsheer S, Nordentoft MS, Schmal C, Keilholz U, Herzel H, Kramer A, Sauter T, Granada AE. Circadian clock features define novel subtypes among breast cancer cells and shape drug sensitivity. Molecular Systems Biology 2025;21:315. DOI: 10.1038/s44320-025-00092-7
| Folder | Description |
|---|---|
Figure2_deep_circadian_phenotyping |
Deep circadian phenotyping pipeline and classification |
Figure3_and_Figure4_pipelines |
Subtype analysis and comparison pipelines |
Figure4_drug_sensitivity_parameter_calculation |
Drug sensitivity metrics and parameter extraction |
- Python 3.8 or later
numpy,scipy,pandas,matplotlib,seaborn- pyBOAT for time-frequency analysis of circadian traces
MIT — see LICENSE. This code was developed by members and collaborators of the Granada Lab research group. For authorship and correspondence, please refer to the publication above.