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Lucian Farcal edited this page Nov 26, 2019 · 30 revisions

This section contains a list of terms or abbreviations with their definition, used in the context of OpenRiskNet project and its infrastructure development: scientific and technical terms, organisations / infrastructures acronyms and projects acronyms.

Scientific and Technical terms

  • AA = Authentication and Authorisation
  • AAI = Authentication and Authorisation Infrastructure
  • AOP = Adverse Outcome Pathway
  • API = Application Programming Interface
  • ASB = Ansible Service broker (OpenShift)
  • AWS = Amazon Web Services
  • BFO = Basic Formal Ontology
  • CD = Continuous Deployment
  • CDK = Chemistry Development Kit
  • CI = Continuous Integration
  • CICD = Continuous Integration and Continuous Deployment
  • CLI = Command-line interface
  • CPU = Central Processing Unit
  • CS = Case Study
  • DoA = Description of Action
  • DoW = Description of Work
  • DPO = Data Protection Officer
  • DW = Data Warehouse
  • ENM = Engineered Nanomaterials
  • GCP = Google Cloud Platform
  • GraphQL = Query language for APIs, and a server-side runtime for executing queries by using a type system defined for the data
  • FAIR = findable, accessible, interoperable and reusable
  • HPC = High Performance Computing
  • HTTP = Hypertext Transfer Protocol
  • HTTPS = Hypertext Transfer Protocol Secure
  • IaaS = Infrastructure as a Service
  • IRI = Internationalized Resource Identifier
  • JSON-LD = JavaScript Object Notation for Linked Data
  • JQ = Jaqpot Quatro
  • KE = Key Event
  • MIE = Molecular Initiating Event
  • NoSQL = Database providing a mechanism for storage and retrieval of data which is modeled in means other than the tabular relations used in relational databases
  • OAuth = Open standard for access delegation, commonly used as a way for Internet users to grant websites or applications access to their information on other websites but without giving them the passwords
  • OECD HT = OECD harmonized templates
  • OKD = Origin Community Distribution (of Kubernetes)
  • OpenID = Open standard and decentralized authentication protocol
  • OWL = Web Ontology Language
  • PBPK = Physiologically based pharmacokinetic
  • PK = Pharmacokinetic
  • POPD = Protection Of Personal Data
  • POSIX = Portable Operating System Interface
  • PostgreSQL = Object-relational database with an emphasis on extensibility and standards compliance
  • QL = Query Language
  • QSAR = Quantitative structure–activity relationship
  • REST = Representational State Transfer
  • RDF = Resource Description Framework
  • SAB = Scientific Advisory Board
  • SOM = Site of metabolism
  • SEND = Standard for Exchange of Nonclinical Data
  • SPARQL = SPARQL Protocol and RDF Query Language
  • SQL = Structured Query Language
  • SRA = Sequence Read Archive
  • SSO = Single sign-on
  • TLS = Transport Layer Security
  • TRL = Technology Readiness Level
  • TSB = Template Service Broker (OpenShift)
  • UC = Use Case
  • URI = Uniform Resource Identifier
  • URL = Uniform Resource Locator
  • VE = Virtual Environment
  • VRE = Virtual Research Environment
  • WP = Work Package

Organisations / infrastructures acronyms

  • CEFIC = European Chemical Industry Council
  • diXa Data Warehouse = A collection of European Toxicogenomics experiments with cross-links to chemical and molecular medicine databases
  • DG CONNECT = The Directorate‑General of EC for Communications Networks, Content and Technology
  • EC = European Commission
  • ECHA = European Chemicals Agency
  • EFPIA = European Federation of Pharmaceutical Industries and Associations
  • EFSA = European Food Safety Authority
  • EGA = The European Genome-phenome Archive
  • EMA = European Medicines Agency
  • EPA = Environmental Protection Agency
  • FDA = Food and Drug Administration in US
  • JRC = Joint Research Centre
  • NSC = European NanoSafety Cluster
  • OECD = Organization for Economic Co-operation and Development
  • SCCS = Scientific Committee on Consumer Safety
  • SSC = Swedish National Infrastructure for Computing (SNIC) Science Cloud

Projects acronyms

  • ACEnano = Analytical and Characterisation Excellence in nanomaterial risk assessment: A tiered approach (EU H2020 Project 2017-2020)
  • EU-ToxRisk = An Integrated European ‘Flagship’ Programme Driving Mechanism-based Toxicity Testing and Risk Assessment for the 21st century (EU H2020 Project 2016 - 2021)
  • eNanoMapper = A Database and Ontology Framework for Nanomaterials Design and Safety Assessment (EU FP7 Project 2014-2017)
  • eTox = Integrating bioinformatics and chemoinformatics approaches for the development of expert systems allowing the in silico prediction of toxicities (EU FP7 Project 2010-2016)
  • HeCaTos - Hepatic and Cardiac Toxicity Systems modelling (EU FP7 Project 2013-2018)
  • NanoCommons - The European Nanotechnology Community Informatics Platform: Bridging data and disciplinary gaps for industry and regulators
  • OpenRiskNet = Open e-Infrastructure to Support Data Sharing, Knowledge Integration and in silico Analysis and Modelling in Risk Assessment (EU H2020 Project 2016-2019)
  • OpenTox = An Open Source Predictive Toxicology Framework (EU FP7 Project 2008-2011)
  • PhenoMeNal - A comprehensive and standardised e-infrastructure for analysing medical metabolic phenotype data (EU H2020 Project 2015-2018)
  • ToxBank = Supporting integrated data analysis and servicing of alternative testing methods in toxicology (EU FP7 Project 2011-2015)

OpenRiskNet case studies

  • DataCure = Data curation and creation of pre-reasoned datasets and searching
  • ModelRX = Modelling for Prediction or Read Across
  • SysGroup = A systems biology approach for grouping compounds
  • MetaP = Metabolism Prediction
  • AOPLink = Identification and Linking of Data related to AOPWiki
  • TGX = Toxicogenomics-based prediction and mechanism identification
  • RevK = Reverse dosimetry and PBPK prediction
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