Discussions

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  Customizable variable modification

  Ning-S211 asked Mar 5, 2026 in Q&A · Unanswered

  

  

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  DIA-NN exited directed after starting the fasta library generation

  TomsonChang-MS asked Mar 4, 2026 in Q&A · Unanswered

  

  

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  Setting values of MS1 and MS2 accuracy for the Orbitrap Astral

  DemianInFocus asked Mar 3, 2026 in Q&A · Answered

  

  

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  Automatic peptidoform scoring

  julia-broadbent asked Mar 2, 2026 in Q&A · Unanswered

  

  

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  Regenerating pr_matrix using the main report

  Milad-Bastami asked Feb 26, 2026 in Q&A · Unanswered

  

  

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  Deep learning-based spectra

  WalterViegener asked Feb 26, 2026 in Q&A · Unanswered

  

  

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  QuantUMS - which peptides are used for protein quantification?

  mpadula asked Feb 24, 2026 in Q&A · Unanswered

  

  

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  Parquet schema for speclib.parquet?

  jpfeuffer asked Feb 24, 2026 in Q&A · Unanswered

  

  

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• #️⃣

  DIA-NN 2.0-series Updates

  vdemichev announced Jan 29, 2025 in DIA-NN versions

  

  

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  MS1 Isotope Abundances

  mtaylor0199 asked Feb 16, 2026 in Q&A · Unanswered

  

  

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  Using an anchor for quantification that has multiple similar isoform

  Leo-Kraljevic asked Feb 17, 2026 in Q&A · Unanswered

  

  

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  Rationale and Benchmarks for TopN = 1 (PG.Quantity) vs PG.MaxLFQ

  AnirudhKashyap511 asked Feb 11, 2026 in Q&A · Unanswered

  

  

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  SILAC var mod

  Elladoron started Feb 10, 2026 in General

  

  

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  Reproducible fragments across fractionated timsTOF runs ; advice?

  AnirudhKashyap511 asked Feb 9, 2026 in Q&A · Answered

  

  

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  ERROR: algorithmic failure: src/diann.cpp: 12000

  edantx asked Jan 27, 2026 in Q&A · Unanswered

  

  

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  Search specific peptides in proteomes

  LKittinun asked Jan 20, 2026 in Q&A · Answered

  

  

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  How to identify/quantify proteins with unique peptides only

  PatrickT2303 asked Aug 4, 2025 in Q&A · Unanswered

  

  

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  DIA-NN Guide: APPTAINER Container for HPC

  florianorenan started Jan 9, 2026 in Show and tell

  

  

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  Normalization strategy for secretome proteomics using DIA-NN and an internal standard

  eva-ferro asked Jan 6, 2026 in Q&A · Answered

  

  

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  Maybe a way to increase protein quantification accuracy

  Chen-proteomics started Dec 19, 2025 in Ideas

  

  

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  PG.Quantity vs PG.maxLFQ

  AnirudhKashyap511 asked Dec 18, 2025 in Q&A · Unanswered

  

  

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  Diann1.9 linux error

  nava20ir asked Dec 15, 2025 in Q&A · Unanswered

  

  

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  Obtaining pr and pg matrices from parquet files

  vm089 asked Dec 1, 2025 in Q&A · Unanswered

  

  

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  SILAC DIANN analysis

  DaliJarboui asked Jun 6, 2025 in Q&A · Unanswered

  

  

  

  

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  Spectral library with pSTY only on the single protein?

  KanshinED1 started Nov 21, 2025 in General

  

  

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